A new tool has been described in the journal Bioinformatics:
All of the words that contribute to the name of this acronym are right there in the article's title. But as this is a JABBA-award-worthy name, we don't expect each word to contribute its first letter (or only one letter):
REDEMPTION: REduced Dimension Ensemble Modeling and Parameter estimaTION
This is certainly far from being the most bogus bioinformatics acronym that I have seen and — as far as I can tell — the name is unique (within the context of bioinformatics). However, I am particularly wary of tools that use a short name which a) has no obvious connection to what the software actually does and b) has potentially emotive associations in other contexts, e.g. religion and/or politics.