10 bioinformatics tools you should be using on Valentines Day

1. HUGS: the database of HUman Genome Sequences

"We envisage that the growth in personal genomics will mean that researchers will increasingly want HUGS to cope with their work."

2. LOVE: LncRNA Ortholog Validation and Evaluation

"If you are unsure as to the quality of your lncRNA annotations, we suggest that you need LOVE."

3. KISSES: Kmers In aSsembled SEquenceS 

"We envisage that KISSES will be widely distributed by people working in the field of genome assembly."

4. HEART: Histidine Enrichment Analysis Report Tool

"Accurate detection of histidine-enriched sequences can be achieved if researchers have HEART."

5. ILOVEYOU: Intergenic LOng VariablE Yeast Operational Units

"Detection of this new class of conserved intergenic element will open new avenues for S. cerevisae researchers, and we predict that many will benefit from a deeper understanding of ILOVEYOUs".

6. ROSESARERED: Random Ortholog SEquence Simulations that ARE REDundant

"This tool effectively generates a series of, largely pointless, simulated ortholog sequences. See also our companion software: ValIdation Of Long Eukaryotic TranscriptS thAt Randomly appEar BioLogically UsEful (VIOLETSAREBLUE)."

7. VALENTINE: VALidation of ENcode Transcriptomes IN Eukaryotes

"We believe that the ENCODE annotations of the human genome are only 80% useful, therefore genome annotators will likely appreciate a VALENTINE."


8. PASSI(ON): Predicting ASSembly Integrity (Or Not)

"Based on our observations, we feel that there is an urgent need for PASSI(ON) within the genomics community."


9. CHOCOLATES: CHOosing COmputationaL AlgoriThms for Testing Evolutionary Simulations

"In a field where which increasingly offers a bewildering choice of bioinformatics tools, we feel that researchers will appreciate CHOCOLATES."

10. SNUGGLES:: SearchiNg for Unique Genes in orGanisms Like Eels and Snakes

"There is a desperate shortage of bioinformatics tools that are dedicated to finding unique genes in creatures that look a bit like worms. Hence we are confident that the community of people who work on snakes, eels, nematodes, and other tubular-like organisms will be receptive to SNUGGLES."