I came across this disturbing image on the web today. Warning, may cause offense:
Even more disturbing was the text that accompanied the image, text that appears on Microsoft Research's flickr account (emphasis mine):
The Microsoft Biology Initiative includes several Microsoft biology tools that enable biology and bioinformatics researchers to be more productive in making scientific discoveries. One such tool, the Microsoft Research Biology Extension for Excel, displays the contents of a FASTA file containing an Influenza A virus sequence. By importing FASTA data into Excel, researchers are better able to visualize and analyze information.
The point at which you want to import FASTA files into Excel is the point at which you should probably think about quitting bioinformatics.